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Protein Target Calculator
Daily protein in grams, calibrated to your goal and training. Special post-GLP-1 mode for adults coming off Ozempic or Mounjaro who need to actively prevent the 25–40% lean-mass loss documented in trial substudies.
Enter your weight to see your daily target.
Targets above the RDA (0.8 g/kg) are well-supported for body composition, satiety, and ageing — Phillips 2016 and the ISSN position stands. Distribute across meals for optimal MPS (Phillips & Van Loon 2011).
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Why protein matters more than the RDA suggests
The RDA of 0.8 g/kg is a floor — the minimum to prevent nitrogen-balance deficiency in healthy adults. It's a long way from optimal. Phillips and colleagues' 2016 review¹Applied Physiology, Nutrition, and Metabolism · 2016Phillips SM, Chevalier S, Leidy HJ — Protein 'requirements' beyond the RDA: implications for optimizing health situates the optimum for body composition, satiety, and ageing at 1.2–1.6 g/kg. Bray's 2012 JAMA inpatient overfeeding study²JAMA · 2012Bray GA et al. — Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating demonstrated directly that low-protein groups gained more fat and less lean mass at matched calories. Cermak's 2012 meta-analysis³American Journal of Clinical Nutrition · 2012Cermak NM et al. — Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis confirmed protein supplementation augments resistance-training adaptations across populations. Weigle 2005⁴American Journal of Clinical Nutrition · 2005Weigle DS et al. — A high-protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations showed increasing protein from 15% to 30% triggered a spontaneous 441 kcal/day reduction in ad-libitum intake — protein leverage in action.
Sources: animal vs plant
Animal proteins (eggs, meat, fish, dairy) are complete and have higher leucine content per gram — relevant for muscle protein synthesis. Plant proteins (legumes, soy, seitan) can hit equivalent total-protein targets but typically require 10–20% more grams to match leucine intake, and combining sources is needed to cover all essential amino acids. Both work; animal sources are more efficient per gram.
Distribute across meals
Phillips and Van Loon's 2011 athlete-protein review⁵Journal of Sports Sciences · 2011Phillips SM, Van Loon LJC — Dietary protein for athletes: from requirements to optimum adaptation established that distributed intake (~0.4 g/kg per meal across 3–4 meals) maximizes muscle protein synthesis vs concentrating it all in one meal. For a 70 kg adult at 1.6 g/kg (112 g/day total), that's ~28 g per meal across 4 meals — roughly 4 oz of meat plus a Greek yogurt at each.
Post-GLP-1 muscle preservation
The Linge 2024 Obesity Reviews substudy⁶Obesity Reviews · 2024Linge J et al. — Body composition and cardiometabolic effects of GLP-1 receptor agonists: changes in lean mass documented that 25–40% of total weight lost on semaglutide is lean mass — a sarcopenia risk especially relevant for women and older adults. The Jensen 2024 JAMA Network Open study⁷JAMA Network Open · 2024Jensen SBK et al. — Bone health after exercise alone, GLP-1 receptor agonist treatment, or combination treatment showed GLP-1 monotherapy reduced bone density at hip and spine; exercise prevented this. The protocol when on or coming off a GLP-1: 1.8–2.0 g/kg protein, distributed across small frequent meals (because appetite is suppressed), plus resistance training 3x/week. Non-negotiable.
Supplements when appropriate
Whey protein is the best-studied and most cost-effective supplemental option; casein has slower digestion useful before sleep; plant blends (pea + rice + hemp) approximate complete amino-acid profiles. Most adults can hit 1.6 g/kg from food alone; supplements help when training intensity is high, when post-GLP-1 appetite is low, or when convenience genuinely beats compliance.
References
- 1.Phillips SM, Chevalier S, Leidy HJ (2016). Protein 'requirements' beyond the RDA: implications for optimizing health. Applied Physiology, Nutrition, and Metabolism. PubMed 26960445
- 2.Bray GA et al. (2012). Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating. JAMA. PubMed 22215165
- 3.Cermak NM et al. (2012). Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis. American Journal of Clinical Nutrition. PubMed 23134885
- 4.Weigle DS et al. (2005). A high-protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations. American Journal of Clinical Nutrition. PubMed 16002798
- 5.Phillips SM, Van Loon LJC (2011). Dietary protein for athletes: from requirements to optimum adaptation. Journal of Sports Sciences. PubMed 22150425
- 6.Linge J et al. (2024). Body composition and cardiometabolic effects of GLP-1 receptor agonists: changes in lean mass. Obesity Reviews. PubMed 38605467
- 7.Jensen SBK et al. (2024). Bone health after exercise alone, GLP-1 receptor agonist treatment, or combination treatment. JAMA Network Open. PubMed 38904957
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